A function for subtelomeric DNA in Saccharomyces cerevisiae.

نویسندگان

  • Arnold B Barton
  • Yuping Su
  • Jacque Lamb
  • Dianna Barber
  • David B Kaback
چکیده

The subtelomeric DNA sequences from chromosome I of Saccharomyces cerevisiae are shown to be inherently poor substrates for meiotic recombination. On the basis of these results and prior observations that crossovers near telomeres do not promote efficient meiosis I segregation, we suggest that subtelomeric sequences evolved to prevent recombination from occurring where it cannot promote efficient segregation.

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عنوان ژورنال:
  • Genetics

دوره 165 2  شماره 

صفحات  -

تاریخ انتشار 2003